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組織相容性復合體蛋白1重組兔單克隆抗體

產(chǎn)品貨號：

BN42146R
中文名稱：

組織相容性復合體蛋白1重組兔單克隆抗體
英文名稱：

Rabbit anti-MHC class I Monoclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN42146R-50ul

50ul

￥2020.00

交叉反應：Human 推薦應用：WB,IHC-P
BN42146R-100ul

100ul

￥3240.00

交叉反應：Human 推薦應用：WB,IHC-P

產(chǎn)品描述

英文名稱	MHC class I
中文名稱	組織相容性復合體蛋白1重組兔單克隆抗體
別名	MHC-1; MHC1; MHC 1; A 28; A 9; Aw 24; Aw 68; CLASS I HISTOCOMPATIBILITY ANTIGEN; H2 K1; H2K; HLA A; HLAA; HLA-A; HLA class I histocompatibility antigen A 1 alpha chain; HLA class I histocompatibility antigen A 11 alpha chain; HLA class I histocompatibility antigen A 2 alpha chain; HLA class I histocompatibility antigen A 24 alpha chain; HLA class I histocompatibility antigen A 3 alpha chain; HLA class I histocompatibility antigen A 30 alpha chain; HLA class I histocompatibility antigen A 32 alpha chain; HLA class I histocompatibility antigen A 68 alpha chain; Major histocompatibility complex class I A; MHC class I heavy chain H2 K; 1A24_HUMAN.
研究領域	腫瘤細胞生物免疫學信號轉(zhuǎn)導轉(zhuǎn)錄調(diào)節(jié)因子細胞分化
抗體來源	Rabbit
克隆類型	Monoclonal
克隆號	10G4
交叉反應	Human,
產(chǎn)品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	40kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human MHC class I:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen. Function: Involved in the presentation of foreign antigens to the immune system. Subunit: Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein (By similarity). Subcellular Location: Cell Membrane; Type I membrane protein. Post-translational modifications: Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity). Similarity: Belongs to the MHC class I family. Contains 1 Ig-like C1-type (immunoglobulin-like) domain. SWISS: P05534 Gene ID: 3105 Database links: Entrez Gene: 3105 Human Omim: 142800 Human SwissProt: P30443 Human Unigene: 181244 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.