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ADAM17重組兔單克隆抗體

產(chǎn)品貨號(hào)：

BN42068R
中文名稱：

ADAM17重組兔單克隆抗體
英文名稱：

Rabbit anti-ADAM17 (9E7) Monoclonal antibody
品牌：

Biorigin

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產(chǎn)品規(guī)格

售價(jià)

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BN42068R-50ul

50ul

￥2020.00

交叉反應(yīng)：Human,Mouse(predicted:Rat) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
BN42068R-100ul

100ul

￥3240.00

交叉反應(yīng)：Human,Mouse(predicted:Rat) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	ADAM17 (9E7)
中文名稱	ADAM17重組兔單克隆抗體
別名	A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADA17_HUMAN.
研究領(lǐng)域	腫瘤免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來(lái)源	Rabbit
克隆類型	Monoclonal
克隆號(hào)	9E7
交叉反應(yīng)	Human, Mouse, (predicted: Rat, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:20-200 IHC-F=1:20-200 ICC=1:20-200 IF=1:20-200 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	93kDa
細(xì)胞定位	細(xì)胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	Recombinant human ADAM17 protein:700-824/824 <Cytoplasmic>
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq]. Subunit: Interacts with MAD2L1, MAPK14 and MUC1. Subcellular Location: Membrane. Tissue Specificity: Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney. Similarity: Contains 1 disintegrin domain. Contains 1 peptidase M12B domain. SWISS: P78536 Gene ID: 6868 Database links: Entrez Gene: 6868 Human Entrez Gene: 11491 Mouse Entrez Gene: 57027 Rat Omim: 603639 Human SwissProt: P78536 Human SwissProt: Q9Z0F8 Mouse SwissProt: Q9Z1K9 Rat Unigene: 404914 Human Unigene: 27681 Mouse Unigene: 144585 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.