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產品描述

英文名稱	P2Y1
中文名稱	P2Y1受體抗體/嘌呤受體抗體
別名	ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1; P2RY1_HUMAN; P2Y1 purinoceptor.
研究領域	信號轉導轉錄調節(jié)因子通道蛋白
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Chicken, Dog, Cow, Horse, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	41kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human P2Y1R:285-373/373
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008] Function: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P47900 Gene ID: 5028 Database links: Entrez Gene: 100135592 Guinea pig Entrez Gene: 5028 Human Entrez Gene: 18441 Mouse Entrez Gene: 25265 Rat Omim: 601167 Human SwissProt: P59902 Guinea pig SwissProt: P47900 Human SwissProt: P49650 Mouse SwissProt: P49651 Rat Unigene: 654526 Human Unigene: 281452 Mouse Unigene: 10217 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. P2Y1 receptor 為離子通道蛋白，一種受體配體開啟的離子通道，介導細胞外核苷酸細胞間信號傳導